A 67-year-old woman presented with metamorphopsia in the right eye.Leopard mottling was seen temporal to the fovea oculus dexter with corresponding hyper- and hypo-autofluorescent lesions on fundus autofluorescence.Spectral domain-optical coherence tomography revealed hyperreflective dots in the retinal pigment motivo walker for sale epithelium and
Background: The t(12;21)(p13;q22), which fuses ETV6 and RUNX1 genes, is the most common genetic abnormality in children with B-cell precursor acute lymphoblastic leukaemia.The implication of the fusion protein in leukemogenesis seems to be clear.However, its role in the maintenance of the disease continues to be controversial.Methods: Generation of
Abstract Inspired by the POLYMOD study, an epidemiological survey was conducted in June 2021 in one of the most densely populated and socially vulnerable sectors of Belo Horizonte (Brazil).A sample d2 gul of 1000 individuals allowed us to identify, within a 24-hour period, the rates of social contacts by age groups, the size and frequency of clique
Cutaneous melanoma arises from the malignant transformation of skin melanocytes; its incidence and mortality have been increasing steadily over the last fifty-years, now representing 3% of total tumors.Once melanoma metastasizes, prognosis is somber and therapeutic options are limited.However, the discovery of prevalent BRAF mutations in at least 5